VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Monk parakeet

Scientific Name: Myiopsitta monachus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Sauropsida-> Sauria-> Archelosauria-> Archosauria-> Dinosauria-> Saurischia-> Theropoda-> Coelurosauria-> Aves-> Neognathae-> Psittaciformes-> Psittacidae-> Myiopsitta

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Severe acute respiratory syndrome coronavirus 2

Family: Coronaviridae

Receptor: NRP1

Receptor NRP1 information

Summary: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Nov 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0060 2021.04 iDrop PBMC Normal 1958 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of NRP1 in human tissues   [NCBI]

Expression: Broad expression in placenta (RPKM 53.3), fat (RPKM 49.6) and 24 other tissues

Protein expression of NRP1 in human tissues   [Proteinatlas]